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AURKB monoclonal antibody, clone ARC0018 

  • Catalog # : MAB22617
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human AURKB.
  • Immunogen:
  • A synthetic peptide corresponding to human AURKB.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (1:50-1:200)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of (1) MCF-7, (2) HepG2, (3) A-549 cell lysates.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of C6 cells. Blue: DAPI for nuclear staining.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 9212
  • Gene Name:
  • AURKB
  • Gene Alias:
  • AIK2,AIM-1,AIM1,ARK2,AurB,IPL1,STK12,STK5
  • Gene Description:
  • aurora kinase B
  • Gene Summary:
  • Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. Aurora kinase B localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A (MIM 603072) localizes to centrosomes (Lampson et al., 2004 [PubMed 14767480]).[supplied by OMIM
  • Other Designations:
  • aurora-1,aurora-B,serine/threonine kinase 12
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