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Last updated: 2020/8/2

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PDGFRB monoclonal antibody, clone ARC0009 

  • Catalog # : MAB22614
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human PDGFRB.
  • Immunogen:
  • A synthetic peptide corresponding to human PDGFRB.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (1:50-1:200)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of (1) SH-SY5Y cell lysates, (2) mouse lung, (3) mouse heart, (4) NIH/3T3 cell lysates.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of NIH/3T3 cells. Blue: DAPI for nuclear staining.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 5159
  • Gene Name:
  • PDGFRB
  • Gene Alias:
  • CD140B,JTK12,PDGF-R-beta,PDGFR,PDGFR1
  • Gene Description:
  • platelet-derived growth factor receptor, beta polypeptide
  • Gene Summary:
  • This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq
  • Other Designations:
  • beta platelet-derived growth factor receptor,platelet-derived growth factor receptor beta,soluble PDGFRb variant 1
  • Interactome
  • Interactome
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