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Mouse Anti-Human (lambda chain) secondary antibody, clone JDC-12 (HRP) 

  • Catalog # : MAB22582
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human lambda light chain.
  • Immunogen:
  • Human lambda light chain.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Human/rhesus lambda.
  • Form:
  • Liquid
  • Conjugation:
  • HRP
  • Purification:
  • Precipitation method and/or chromatography purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • ELISA (1:1000-2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (50% glycerol).
  • Storage Instruction:
  • Store at 4°C.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA plate was coated with purified human IgG kappa, IgM kappa, IgA kappa, IgG lambda, IgM lambda, and IgA lambda. Immunoglobulins were detected with serially diluted Mouse Anti-Human (lambda chain) secondary antibody, clone JDC-12 (HRP).
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
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  • Gene Information
  • Entrez GeneID:
  • 3535
  • Protein Accession#:
  • P0CG04; P0DOY2; P0DOY3; A0M8Q6
  • Gene Name:
  • IGL@
  • Gene Alias:
  • IGL,MGC88804
  • Gene Description:
  • immunoglobulin lambda locus
  • Gene Summary:
  • Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. [provided by RefSeq
  • Other Designations:
  • immunoglobulin lambda gene cluster
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