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Last updated: 2020/5/24

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UHRF1 monoclonal antibody (Biotin) 

  • Catalog # : MAB22410
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human UHRF1.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 1-408 at the N-terminus of human UHRF1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Conjugation:
  • Biotin
  • Storage Buffer:
  • In 0.01 M Na3PO4, 0.25 M NaCl, pH 7.6 (5 mg/mL BSA, 0.02% sodium azide).
  • Storage Instruction:
  • Store in the dark at 4°C for six months.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Gene Information
  • Gene Name:
  • UHRF1
  • Gene Alias:
  • FLJ21925,ICBP90,MGC138707,Np95,RNF106,hNP95
  • Gene Description:
  • ubiquitin-like with PHD and ring finger domains 1
  • Gene Summary:
  • This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • E3 ubiquitin-protein ligase UHRF1,RING finger protein 106,inverted CCAAT box-binding protein of 90 kDa,nuclear zinc finger protein Np95,transcription factor ICBP90,ubiquitin-like, containing PHD and RING finger domains, 1
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