CNTNAP1 monoclonal antibody, clone ACEI-3
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of U87 MG cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human CNTNAP1.
Immunogen
A synthetic peptide corresponding to human CNTNAP1.
Host
Rabbit
Reactivity
Human
Specificity
The antibody reacts with human CNTNAP1, in native form and recombinant. Superfamily members of CNTNAP1 are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of U87 MG cell lysate.Immunohistochemistry
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Gene Info — CNTNAP1
Entrez GeneID
8506Protein Accession#
P78357Gene Name
CNTNAP1
Gene Alias
CASPR, CNTNAP, NRXN4, P190
Gene Description
contactin associated protein 1
Omim ID
602346Gene Ontology
HyperlinkGene Summary
The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq
Other Designations
neurexin 4
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Interactome
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Pathway
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Disease
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