USP11 monoclonal antibody, clone ADCC-21
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human USP11.
Immunogen
A synthetic peptide corresponding to human USP11.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
The antibody reacts with human, mouse USP11, in native form and recombinant. Superfamily members of USP11 are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:200)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunoprecipitation (1:100)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: HEK293 cell lysate; Lane 2: Mouse testis lysate.Immunocytochemistry
Immunofluorescence
Immunoprecipitation
Flow Cytometry
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Gene Info — USP11
Entrez GeneID
8237Protein Accession#
P51784Gene Name
USP11
Gene Alias
UHX1
Gene Description
ubiquitin specific peptidase 11
Omim ID
300050Gene Ontology
HyperlinkGene Summary
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq
Other Designations
deubiquitinating enzyme 11|ubiquitin carboxyl-terminal hydrolase, X-linked|ubiquitin specific protease 11|ubiquitin thiolesterase 11|ubiquitin-specific processing protease 11
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