H2AFY monoclonal antibody, clone ADDI-8
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human H2AFY.
Immunogen
A synthetic peptide corresponding to human H2AFY.
Host
Rabbit
Reactivity
Human
Specificity
The antibody reacts with human H2AFY, in native form and recombinant. Superfamily members of H2AFY are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:1000-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate.Immunohistochemistry
Immunocytochemistry
Immunofluorescence
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Gene Info — H2AFY
Entrez GeneID
9555Protein Accession#
O75367Gene Name
H2AFY
Gene Alias
H2A.y, H2A/y, H2AF12M, H2AFJ, MACROH2A1.1, mH2A1, macroH2A1.2
Gene Description
H2A histone family, member Y
Omim ID
610054Gene Ontology
HyperlinkGene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
histone macroH2A1.1|histone macroH2A1.2
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