PARD6A monoclonal antibody, clone AEDE-16
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Jurkat cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human PARD6A.
Immunogen
A synthetic peptide corresponding to human PARD6A.
Host
Rabbit
Reactivity
Human
Specificity
The antibody reacts with human PARD6A, in native form and recombinant. Superfamily members of PARD6A are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Jurkat cell lysate.Immunoprecipitation
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Gene Info — PARD6A
Entrez GeneID
50855Protein Accession#
Q9NPB6Gene Name
PARD6A
Gene Alias
PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
Gene Description
par-6 partitioning defective 6 homolog alpha (C. elegans)
Omim ID
607484Gene Ontology
HyperlinkGene Summary
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
Tax-interacting protein 40|par-6 partitioning defective 6 homolog alpha|partitioning defective-6 homolog alpha|partitioning-defective protein 6
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Interactome
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Pathway
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Disease
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