NPR3 monoclonal antibody, clone AEDH-14
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human NPR3.
Immunogen
A synthetic peptide corresponding to human NPR3.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with humant NPR3, in native form and recombinant. Superfamily members of NPR3 are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:100)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of NPR3 in HeLa cell lysate.Flow Cytometry
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Gene Info — NPR3
Entrez GeneID
4883Protein Accession#
P17342Gene Name
NPR3
Gene Alias
ANPRC, GUCY2B, NPRC
Gene Description
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
Omim ID
108962Gene Ontology
HyperlinkGene Summary
The family of natriuretic peptides (see MIM 108780) elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.[supplied by OMIM
Other Designations
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Interactome
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Disease
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