PPIF monoclonal antibody, clone ACGO-16
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human PPIF.
Immunogen
A synthetic peptide corresponding to human PPIF.
Host
Rabbit
Reactivity
Human
Specificity
The antibody reacts with human PPIF, in native form and recombinant. Superfamily members of PPIF are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunoprecipitation (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate.Immunohistochemistry
Immunoprecipitation
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Gene Info — PPIF
Entrez GeneID
10105Protein Accession#
P30405Gene Name
PPIF
Gene Alias
CYP3, Cyp-D, FLJ90798, MGC117207
Gene Description
peptidylprolyl isomerase F
Omim ID
604486Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq
Other Designations
OTTHUMP00000019925|PPIase|cyclophilin 3|cyclophilin D|cyclophilin F|peptidyl-prolyl cis-trans isomerase, mitochondral|rotamase
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Interactome
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Disease
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