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Last updated: 2021/8/8

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COIL monoclonal antibody, clone AFDC-3 

  • Catalog # : MAB22231
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human COIL.
  • Immunogen:
  • A synthetic peptide corresponding to human COIL.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • The antibody reacts with human COIL, in native form and recombinant. Superfamily members of COIL are not reactive to this antibody.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Flow Cytometry (1:100)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C for short term storage. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Jurkat cell lysate.
  • Flow Cytometry
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 8161
  • Gene Name:
  • COIL
  • Gene Alias:
  • CLN80,p80-coilin
  • Gene Description:
  • coilin
  • Gene Summary:
  • The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq
  • Other Designations:
  • coilin p80
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