Rabbit monoclonal antibody raised against synthetic peptide of human LPAR1.
Immunogen:
A synthetic peptide corresponding to human LPAR1.
Host:
Rabbit
Reactivity:
Human
Specificity:
The antibody reacts with human LPAR1, in native form and recombinant. Superfamily members of LPAR1 are not reactive to this antibody.
Form:
Liquid
Purification:
Affinity purification
Isotype:
IgG
Recommend Usage:
Immunohistochemistry (1:50-1:200) Immunoprecipitation (1:50) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction:
Store at 4°C for short term storage. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq
Other Designations:
OTTHUMP00000021903,OTTHUMP00000021904,OTTHUMP00000021905,endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2,ventricular zone gene 1