LPAR1 monoclonal antibody, clone ACGE-12
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More Files
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human LPAR1.
Immunogen
A synthetic peptide corresponding to human LPAR1.
Host
Rabbit
Reactivity
Human
Specificity
The antibody reacts with human LPAR1, in native form and recombinant. Superfamily members of LPAR1 are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunoprecipitation (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of A-375 cell lysate.Immunohistochemistry
Immunoprecipitation
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Gene Info — LPAR1
Entrez GeneID
1902Protein Accession#
Q92633Gene Name
LPAR1
Gene Alias
EDG2, GPR26, Gpcr26, LPA1, Mrec1.3, VZG1, edg-2, rec.1.3, vzg-1
Gene Description
lysophosphatidic acid receptor 1
Omim ID
602282Gene Ontology
HyperlinkGene Summary
The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq
Other Designations
OTTHUMP00000021903|OTTHUMP00000021904|OTTHUMP00000021905|endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2|ventricular zone gene 1
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Interactome
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