HPGD monoclonal antibody, clone AEFF-8
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More Files
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human HPGD.
Immunogen
A synthetic peptide corresponding to human HPGD.
Host
Rabbit
Reactivity
Human
Specificity
The antibody reacts with human HPGD, in native form and recombinant. Superfamily members of HPGD are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:60)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of SW480 cell lysate.Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — HPGD
Entrez GeneID
3248Protein Accession#
P15428Gene Name
HPGD
Gene Alias
15-PGDH, PGDH, PGDH1, SDR36C1
Gene Description
hydroxyprostaglandin dehydrogenase 15-(NAD)
Omim ID
601688Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
15-hydroxy prostaglandin dehydrogenase|15-hydroxyprostaglandin dehydrogenase|NAD+-dependent 15-hydroxyprostaglandin dehydrogenase|short chain dehydrogenase/reductase family 36C, member 1
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Interactome
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Disease
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