LOXL2 monoclonal antibody, clone ADBD-12
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of MCF-7 cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human LOXL2.
Immunogen
A synthetic peptide corresponding to human LOXL2.
Host
Rabbit
Reactivity
Human
Specificity
The antibody reacts with human LOXL2, in native form and recombinant. Superfamily members of LOXL2 are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of MCF-7 cell lysate.Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — LOXL2
Entrez GeneID
4017Protein Accession#
Q9Y4K0Gene Name
LOXL2
Gene Alias
LOR2, WS9-14
Gene Description
lysyl oxidase-like 2
Omim ID
606663Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq
Other Designations
lysyl oxidase homolog 2|lysyl oxidase related 2
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Interactome
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Disease
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