PHOX2B monoclonal antibody, clone AEFG-16
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of Neuro-2a cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human PHOX2B.
Immunogen
A synthetic peptide corresponding to human PHOX2B.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody reacts with human, mouse PHOX2B, in native form and recombinant. Superfamily members of PHOX2B are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of Neuro-2a cell lysate. -
Gene Info — PHOX2B
Entrez GeneID
8929Protein Accession#
Q99453Gene Name
PHOX2B
Gene Alias
NBPhox, PMX2B
Gene Description
paired-like homeobox 2b
Gene Ontology
HyperlinkGene Summary
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq
Other Designations
PHOX2B homeodomain protein|neuroblastoma paired-type homeobox protein|paired mesoderm homeobox 2b
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Disease
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