CRX monoclonal antibody, clone AFIO-3
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of Y-79 cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human CRX.
Immunogen
A synthetic peptide corresponding to human CRX.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human CRX, in native form and recombinant. Superfamily members of CRX are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of Y-79 cell lysate. -
Gene Info — CRX
Entrez GeneID
1406Protein Accession#
O43186Gene Name
CRX
Gene Alias
CORD2, CRD, LCA7, OTX3
Gene Description
cone-rod homeobox
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
cone-rod homeobox protein|orthodenticle homeobox 3
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Interactome
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Disease
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