RELN monoclonal antibody, clone ACFE-18
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human RELN.
Immunogen
A synthetic peptide corresponding to human RELN.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human, rat RELN, in native form and recombinant. Superfamily members of RELN are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of HepG2 cell lysate. -
Gene Info — RELN
Entrez GeneID
5649Protein Accession#
P78509Gene Name
RELN
Gene Alias
PRO1598, RL
Gene Description
reelin
Gene Ontology
HyperlinkGene Summary
This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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