DAZL monoclonal antibody, clone ACBF-4
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot (tissue lysate) analysis of human testis lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human DAZL.
Immunogen
A synthetic peptide corresponding to human DAZL.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human DAZL, in native form and recombinant. Superfamily members of DAZL are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot (tissue lysate) analysis of human testis lysate. -
Gene Info — DAZL
Entrez GeneID
1618Protein Accession#
Q92904Gene Name
DAZL
Gene Alias
DAZH, DAZL1, DAZLA, MGC26406, SPGYLA
Gene Description
deleted in azoospermia-like
Omim ID
601486Gene Ontology
HyperlinkGene Summary
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. [provided by RefSeq
Other Designations
deleted in azoospermia-like autosomal|germline specific RNA binding protein|spermatogenesis gene on the Y-like autosomal
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Interactome
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Disease
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