RRM2 monoclonal antibody, clone AEAE-18
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human RRM2.
Immunogen
A synthetic peptide corresponding to human RRM2.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human RRM2, in native form and recombinant. Superfamily members of RRM2 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of HeLa cell lysate. -
Gene Info — RRM2
Entrez GeneID
6241Protein Accession#
P31350Gene Name
RRM2
Gene Alias
R2, RR2M
Gene Description
ribonucleotide reductase M2 polypeptide
Omim ID
180390Gene Ontology
HyperlinkGene Summary
This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq
Other Designations
ribonucleotide reductase M2 subunit
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Interactome
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