RARB monoclonal antibody, clone AEHH-18
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human RARB.
Immunogen
A synthetic peptide corresponding to human RARB.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human RARB, in native form and recombinant. Superfamily members of RARB are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of MCF7 cell lysate. -
Gene Info — RARB
Entrez GeneID
5915Protein Accession#
P10826Gene Name
RARB
Gene Alias
HAP, NR1B2, RRB2
Gene Description
retinoic acid receptor, beta
Omim ID
180220Gene Ontology
HyperlinkGene Summary
This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined. [provided by RefSeq
Other Designations
HBV-activated protein|RAR-epsilon|hepatitis B virus activated protein|retinoic acid receptor beta 2|retinoic acid receptor beta 4|retinoic acid receptor beta 5|retinoic acid receptor, beta polypeptide
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Interactome
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Disease
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