COPS5 monoclonal antibody, clone AEEG-3
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of MCF-7 cell lysate.
-
Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human COPS5.
Immunogen
A synthetic peptide corresponding to human COPS5.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human, mouse, rat COPS5, in native form and recombinant. Superfamily members of COPS5 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of MCF-7 cell lysate. -
Gene Info — COPS5
Entrez GeneID
10987Protein Accession#
Q92905Gene Name
COPS5
Gene Alias
CSN5, JAB1, MGC3149, MOV-34, SGN5
Gene Description
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
Omim ID
604850Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq
Other Designations
38 kDa Mov34 homolog|COP9 signalosome subunit 5|Jun activation domain-binding protein
-
Interactome
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com