PDCD6IP monoclonal antibody, clone AEBO-16
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of K-562 cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human PDCD6IP.
Immunogen
A synthetic peptide corresponding to human PDCD6IP.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human, mouse, rat PDCD6IP, in native form and recombinant. Superfamily members of PDCD6IP are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of K-562 cell lysate. -
Gene Info — PDCD6IP
Entrez GeneID
10015Protein Accession#
Q8WUM4Gene Name
PDCD6IP
Gene Alias
AIP1, Alix, DRIP4, HP95, MGC17003
Gene Description
programmed cell death 6 interacting protein
Omim ID
608074Gene Ontology
HyperlinkGene Summary
This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ALG-2 interacting protein 1|ALG-2 interacting protein X|apoptosis-linked gene 2-interacting protein X|dopamine receptor interacting protein 4|programmed cell death 6-interacting protein
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Interactome
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Pathway
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Disease
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