PAK2 monoclonal antibody, clone ADFE-16

Catalog # MAB22147

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western blot analysis of HeLa cell lysate.

  • Specification

    Product Description

    Rabbit monoclonal antibody raised against synthetic peptide of human PAK2.

    Immunogen

    A synthetic peptide corresponding to human PAK2.

    Host

    Rabbit

    Reactivity

    Human

    Specificity

    The antibody reacts with human PAK2, in native form and recombinant. Superfamily members of PAK2 are not reactive to this antibody.

    Form

    Liquid

    Purification

    Affinity purification

    Isotype

    IgG

    Recommend Usage

    Flow Cytometry (1:80)
    Immunocytochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    Immunohistochemistry (1:100-1:500)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).

    Storage Instruction

    Store at 4°C for short term storage. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    Western blot analysis of HeLa cell lysate.

    Immunohistochemistry

    Immunocytochemistry

    Immunofluorescence

    Flow Cytometry

  • Gene Info — PAK2

    Entrez GeneID

    5062

    Protein Accession#

    Q13177

    Gene Name

    PAK2

    Gene Alias

    PAK65, PAKgamma

    Gene Description

    p21 protein (Cdc42/Rac)-activated kinase 2

    Omim ID

    605022

    Gene Ontology

    Hyperlink

    Gene Summary

    The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq

    Other Designations

    S6/H4 kinase|p21 (CDKN1A)-activated kinase 2|p21-activated kinase 2

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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