ITK monoclonal antibody, clone ACAB-9
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Jurkat cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human ITK.
Immunogen
A synthetic peptide corresponding to human ITK.
Host
Rabbit
Reactivity
Human
Specificity
The antibody reacts with human ITK, in native form and recombinant. Superfamily members of ITK are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:60)
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Jurkat cell lysate.Immunohistochemistry
Flow Cytometry
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Gene Info — ITK
Entrez GeneID
3702Protein Accession#
Q08881Gene Name
ITK
Gene Alias
EMT, LYK, MGC126257, MGC126258, PSCTK2
Gene Description
IL2-inducible T-cell kinase
Omim ID
186973Gene Ontology
HyperlinkGene Summary
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq
Other Designations
homolog of mouse T-cell itk/tsk|tyrosine-protein kinase ITK/TSK|tyrosine-protein kinase LYK
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Interactome
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Pathway
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Disease
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