XPO1 monoclonal antibody, clone AEFD-24
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Hela cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human XPO1.
Immunogen
A synthetic peptide corresponding to human XPO1.
Host
Rabbit
Reactivity
Human
Specificity
The antibody reacts with human XPO1, in native form and recombinant. Superfamily members of XPO1 are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:100)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Hela cell lysate.Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — XPO1
Entrez GeneID
7514Protein Accession#
O14980Gene Name
XPO1
Gene Alias
CRM1, DKFZp686B1823
Gene Description
exportin 1 (CRM1 homolog, yeast)
Omim ID
602559Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq
Other Designations
CRM1, yeast, homolog|Exportin-1 (required for chromosome region maintenance)|exportin 1|exportin 1 (CRM1, yeast, homolog)
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Interactome
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