BIRC2 monoclonal antibody, clone ABIG-2
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of HepG2 cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human BIRC2.
Immunogen
A synthetic peptide corresponding to human BIRC2.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human BIRC2, in native form and recombinant. Superfamily members of BIRC2 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-200)
Immunofluorescence (1:50-200)
Immunocytochemistry (1:50-200)
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of HepG2 cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Immunofluorescence
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Gene Info — BIRC2
Entrez GeneID
329Protein Accession#
Q13490Gene Name
BIRC2
Gene Alias
API1, HIAP2, Hiap-2, MIHB, RNF48, cIAP1
Gene Description
baculoviral IAP repeat-containing 2
Omim ID
601712Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. [provided by RefSeq
Other Designations
NFR2-TRAF signalling complex protein|apoptosis inhibitor 1|baculoviral IAP repeat-containing protein 2
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Interactome
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Pathway
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Disease
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