TACR1 monoclonal antibody, clone AFBH-20
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of K-562 cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human TACR1.
Immunogen
A synthetic peptide corresponding to human TACR1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody reacts with human, mouse, rat TACR1, in native form and recombinant. Superfamily members of TACR1 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:50)
Western Blot (1:1000-5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of K-562 cell lysate.Immunoprecipitation
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Gene Info — TACR1
Entrez GeneID
6869Protein Accession#
P25103Gene Name
TACR1
Gene Alias
NK1R, NKIR, SPR, TAC1R
Gene Description
tachykinin receptor 1
Omim ID
162323Gene Ontology
HyperlinkGene Summary
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq
Other Designations
NK-1 receptor|neurokinin 1 receptor|tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor)|tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
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Interactome
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Pathway
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Disease
- Alcoholism
- Anorexia Nervosa
- Asthma
- Bipolar Disorder
- Bulimia
- Chronic Disease
- Constipation
- Cough
- Endometriosis
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