PMP22 monoclonal antibody, clone ACIC-16
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human PMP22.
Immunogen
A synthetic peptide corresponding to human PMP22.
Host
Rabbit
Reactivity
Human, Rat
Specificity
This antibody reacts with human, rat PMP22, in native form and recombinant. Superfamily members of PMP22 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of 293T cell lysate. -
Gene Info — PMP22
Entrez GeneID
5376Protein Accession#
Q01453Gene Name
PMP22
Gene Alias
CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, MGC20769, Sp110
Gene Description
peripheral myelin protein 22
Gene Ontology
HyperlinkGene Summary
This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing of this gene results in three transcript variants that encode the same protein. [provided by RefSeq
Other Designations
growth arrest-specific 3
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Interactome
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Disease
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