NCOA1 monoclonal antibody, clone AEHD-14
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More Files
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human NCOA1.
Immunogen
A synthetic peptide corresponding to human NCOA1.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human NCOA1, in native form and recombinant. Superfamily members of NCOA1 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-200)
Immunoprecipitation (1:50)
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of HEK293 cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
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Gene Info — NCOA1
Entrez GeneID
8648Protein Accession#
Q15788Gene Name
NCOA1
Gene Alias
F-SRC-1, KAT13A, MGC129719, MGC129720, NCoA-1, RIP160, SRC-1, SRC1, bHLHe42, bHLHe74
Gene Description
nuclear receptor coactivator 1
Omim ID
602691Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
Hin-2 protein|OTTHUMP00000155183|PAX3/NCOA1 fusion protein|steroid receptor coactivator-1
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Interactome
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Disease
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