YY1 monoclonal antibody, clone AIE-25
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More Files
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human YY1.
Immunogen
A synthetic peptide corresponding to human YY1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody reacts with human, mouse, rat YY1, in native form and recombinant. Superfamily members of YY1 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-200)
Immunofluorescence (1:100-500)
Immunocytochemistry (1:100-500)
Immunoprecipitation (1:50-100)
Western Blot (1:500-3000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of (1) HeLa, (2) Daudi cell lysates.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bladder.Immunocytochemistry
Immunofluorescence
Immunoprecipitation
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Gene Info — YY1
Entrez GeneID
7528Protein Accession#
P25490Gene Name
YY1
Gene Alias
DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1
Gene Description
YY1 transcription factor
Omim ID
600013Gene Ontology
HyperlinkGene Summary
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq
Other Designations
INO80 complex subunit S|Yin and Yang 1 protein
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Interactome
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Disease
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