TRPM7 monoclonal antibody, clone ADGD-20
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human TRPM7.
Immunogen
A synthetic peptide corresponding to human TRPM7.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody reacts with human, mouse, rat TRPM7, in native form and recombinant. Superfamily members of TRPM7 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:100)
Immunofluorescence (1:50-200)
Immunocytochemistry (1:50-200)
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of HeLa cell lysate.Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — TRPM7
Entrez GeneID
54822Protein Accession#
Q96QT4Gene Name
TRPM7
Gene Alias
CHAK, CHAK1, FLJ20117, FLJ25718, LTRPC7, TRP-PLIK
Gene Description
transient receptor potential cation channel, subfamily M, member 7
Gene Ontology
HyperlinkGene Summary
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM
Other Designations
LTRPC ion channel family member 7
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Interactome
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