TERF2 monoclonal antibody, clone AFOB-20
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human TERF2.
Immunogen
A synthetic peptide corresponding to human TERF2.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human TERF2, in native form and recombinant. Superfamily members of TERF2 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-200)
Immunofluorescence (1:50-200)
Immunocytochemistry (1:50-200)
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of Jurkat cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Immunofluorescence
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Gene Info — TERF2
Entrez GeneID
7014Protein Accession#
Q15554Gene Name
TERF2
Gene Alias
TRBF2, TRF2
Gene Description
telomeric repeat binding factor 2
Omim ID
602027Gene Ontology
HyperlinkGene Summary
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq
Other Designations
telomeric repeat binding protein 2
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Interactome
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Disease
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