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ALDH2 monoclonal antibody, clone AFOI-1 

  • Catalog # : MAB22057
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic protein of human ALDH2.
  • Immunogen:
  • A synthetic peptide corresponding to human ALDH2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody reacts with human, mouse, rat ALDH2, in native form and recombinant. Superfamily members of ALDH2 are not reactive to antibody.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-200)
    Immunofluorescence (1:50-200)
    Immunocytochemistry (1:50-200)
    Immunoprecipitation (1:50)
    Western Blot (1:500-2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot (cell lysate) analysis of HepG2 cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunocytochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunocytochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 217
  • Gene Name:
  • ALDH2
  • Gene Alias:
  • ALDH-E2,ALDHI,ALDM,MGC1806
  • Gene Description:
  • aldehyde dehydrogenase 2 family (mitochondrial)
  • Gene Summary:
  • This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq
  • Other Designations:
  • ALDH class 2,acetaldehyde dehydrogenase 2,liver mitochondrial ALDH,mitochondrial aldehyde dehydrogenase 2,nucleus-encoded mitochondrial aldehyde dehydrogenase 2
  • Related Disease
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