PON1 monoclonal antibody, clone ACAG-16
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human PON1.
Immunogen
A synthetic peptide corresponding to human PON1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody reacts with human, mouse, rat PON1, in native form and recombinant. Superfamily members of PON1 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:50)
Western Blot (1:1000-5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot (tissue lysate) analysis of human plasma lysate.Immunoprecipitation
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Gene Info — PON1
Entrez GeneID
5444Protein Accession#
P27169Gene Name
PON1
Gene Alias
ESA, PON
Gene Description
paraoxonase 1
Omim ID
168820Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq
Other Designations
arylesterase B-type|esterase A|paraoxonase B-type|serum aryldiakylphosphatase
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Interactome
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