Bcl3 monoclonal antibody, clone 150-3.5
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Specification
Product Description
Hamster monoclonal antibody raised against recombinant Bcl3.
Immunogen
Recombinant His fusion protein corresponding to mouse Bcl3.
Host
Hamster
Reactivity
Human, Mouse
Specificity
This antibody recognizes human and mouse Bcl-3.
Form
Liquid
Isotype
IgG
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — Bcl3
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Publication Reference
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Immunological adjuvants promote activated T cell survival via induction of Bcl-3.
Mitchell TC, Hildeman D, Kedl RM, Teague TK, Schaefer BC, White J, Zhu Y, Kappler J, Marrack P.
Nature Immunology 2001 May; 2(5):397.
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Regulation of NFKB1 proteins by the candidate oncoprotein BCL-3: generation of NF-kappaB homodimers from the cytoplasmic pool of p50-p105 and nuclear translocation.
Watanabe N, Iwamura T, Shinoda T, Fujita T.
The EMBO Journal 1997 Jun; 16(12):3609.
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The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner.
Nolan GP, Fujita T, Bhatia K, Huppi C, Liou HC, Scott ML, Baltimore D.
Molecular and Cellular Biology 1993 Jun; 13(6):3557.
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Immunological adjuvants promote activated T cell survival via induction of Bcl-3.
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