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Last updated: 2016/12/4
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NCOA3 monoclonal antibody

  • Catalog # : MAB2171
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of NCOA3.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human NCOA3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody recognizes human AIB1, a 160 kD protein and member of the SRC-1 family of nuclear receptor coactivators.
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 8202
  • Gene Name:
  • NCOA3
  • Gene Alias:
  • ACTR,AIB-1,AIB1,CAGH16,CTG26,KAT13B,MGC141848,RAC3,SRC3,TNRC14,TNRC16,TRAM-1,bHLHe42,pCIP
  • Gene Description:
  • nuclear receptor coactivator 3
  • Gene Summary:
  • The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq
  • Other Designations:
  • CBP-interacting protein,OTTHUMP00000031716,OTTHUMP00000031718,amplified in breast cancer-1,receptor-associated coactivator 3,steroid receptor coactivator protein 3,thyroid hormone receptor activator molecule 1
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