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Last updated: 2021/6/13

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PTGIS monoclonal antibody, clone 3C8 

  • Catalog # : MAB21517
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human PTGIS.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    The optimal working dilution should be determined by the end user.
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 5740
  • Gene Name:
  • PTGIS
  • Gene Alias:
  • CYP8,CYP8A1,MGC126858,MGC126860,PGIS,PTGI
  • Gene Description:
  • prostaglandin I2 (prostacyclin) synthase
  • Gene Summary:
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031777,cytochrome P450, family 8, subfamily A, polypeptide 1
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