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PTPN13 monoclonal antibody, clone T32-7G5 

  • Catalog # : MAB21514
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant human PTPN13.
  • Immunogen:
  • Recombinant protein corresponding to human PTPN13.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • Western Blot (1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 0.15M NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5783
  • Gene Name:
  • PTPN13
  • Gene Alias:
  • DKFZp686J1497,FAP-1,PNP1,PTP-BAS,PTP-BL,PTP1E,PTPL1,PTPLE
  • Gene Description:
  • protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq
  • Other Designations:
  • APO-1/CD95 (Fas)-associated phosphatase,Fas-associated phosphatase-1,protein tyrosine phosphatase 1E,protein tyrosine phosphatase, non-receptor type 13,protein tyrosine phosphatase, nonreceptor type 13,protein-tyrosine phosphatase 1, Fas-associated,protei
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