LRDD monoclonal antibody, clone 3C5G8
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: LRDD-hIgGFc transfected HEK293 cell lysates with LRDD monoclonal antibody, clone 3C5G8 (Cat # MAB21507).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with LRDD monoclonal antibody, clone 3C5G8 (Cat # MAB21507).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human LRDD.
Immunogen
Recombinant protein corresponding to amino acids 776-910 of human LRDD.
Host
Mouse
Theoretical MW (kDa)
99.7
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: LRDD-hIgGFc transfected HEK293 cell lysates with LRDD monoclonal antibody, clone 3C5G8 (Cat # MAB21507).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with LRDD monoclonal antibody, clone 3C5G8 (Cat # MAB21507). -
Gene Info — LRDD
Entrez GeneID
55367Protein Accession#
Q9HB75Gene Name
LRDD
Gene Alias
DKFZp434D229, MGC16925, PIDD
Gene Description
leucine-rich repeats and death domain containing
Omim ID
605247Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
leucine rich repeat and death domain containing protein|leucine-rich and death domain containing
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Interactome
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Pathway
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