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Last updated: 2021/6/13

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LRDD monoclonal antibody, clone 3C5G8 

  • Catalog # : MAB21507
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human LRDD.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 776-910 of human LRDD.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 99.7
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of Lane 1: HEK293 and Lane 2: LRDD-hIgGFc transfected HEK293 cell lysates with LRDD monoclonal antibody, clone 3C5G8 (Cat # MAB21507).
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis with LRDD monoclonal antibody, clone 3C5G8 (Cat # MAB21507).
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Gene Name:
  • LRDD
  • Gene Alias:
  • DKFZp434D229,MGC16925,PIDD
  • Gene Description:
  • leucine-rich repeats and death domain containing
  • Gene Summary:
  • The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • leucine rich repeat and death domain containing protein,leucine-rich and death domain containing
  • Gene Pathway
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