MLL3 monoclonal antibody, clone 6D1B9
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human MLL3.
Immunogen
Recombinant protein corresponding to amino acids 1-205 of human MLL3.
Host
Mouse
Theoretical MW (kDa)
541.4
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Immunocytochemistry (1:200-1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:1000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: MLL3-hIgGFc transfected HEK293 cell lysates with MLL3 monoclonal antibody, clone 6D1B9 (Cat # MAB21488).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervix cancer with MLL3 monoclonal antibody, clone 6D1B9 (Cat # MAB21488).Immunocytochemistry
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with MLL3 monoclonal antibody, clone 6D1B9 (Cat # MAB21488).Flow Cytometry
Flow cytometric analysis of HeLa cells with MLL3 monoclonal antibody, clone 6D1B9 (Cat # MAB21488) (Green). Red: Negative Control. -
Gene Info — MLL3
Entrez GeneID
58508Protein Accession#
Q8NEZ4Gene Name
MLL3
Gene Alias
DKFZp686C08112, FLJ12625, FLJ38309, HALR, KIAA1506, KMT2C, MGC119851, MGC119852, MGC119853
Gene Description
myeloid/lymphoid or mixed-lineage leukemia 3
Omim ID
606833Gene Ontology
HyperlinkGene Summary
This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq
Other Designations
ALR-like protein|histone-lysine N-methyltransferase, H3 lysine-4 specific
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Interactome
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Disease
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