PVRL3 monoclonal antibody, clone 6D5B2
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human PVRL3.
Immunogen
Recombinant protein corresponding to amino acids 282-404 of human PVRL3.
Host
Mouse
Theoretical MW (kDa)
61
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: PVRL3-hIgGFc transfected HEK293 cell lysates with PVRL3 monoclonal antibody, clone 6D5B2 (Cat # MAB21475).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with PVRL3 monoclonal antibody, clone 6D5B2 (Cat # MAB21475).Flow Cytometry
Flow cytometric analysis of HL-60 cells with PVRL3 monoclonal antibody, clone 6D5B2 (Cat # MAB21475) (Green). Red: Negative Control. -
Gene Info — PVRL3
Entrez GeneID
25945Protein Accession#
Q9NQS3Gene Name
PVRL3
Gene Alias
CD113, CDw113, DKFZp566B0846, FLJ90624, PPR3, PRR3, PVRR3, nectin-3
Gene Description
poliovirus receptor-related 3
Omim ID
607147Gene Ontology
HyperlinkGene Summary
Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.[supplied by OMIM
Other Designations
nectin 3
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Interactome
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Pathway
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Disease
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