NFKB2 monoclonal antibody, clone 5E6A12
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: NFKB2-hIgGFc transfected HEK293 cell lysates with NFKB2 monoclonal antibody, clone 5E6A12 (Cat # MAB21463).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with NFKB2 monoclonal antibody, clone 5E6A12 (Cat # MAB21463).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human NFKB2.
Immunogen
Recombinant protein corresponding to amino acids 712-900 of human NFKB2.
Host
Mouse
Theoretical MW (kDa)
96.7
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: NFKB2-hIgGFc transfected HEK293 cell lysates with NFKB2 monoclonal antibody, clone 5E6A12 (Cat # MAB21463).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with NFKB2 monoclonal antibody, clone 5E6A12 (Cat # MAB21463). -
Gene Info — NFKB2
Entrez GeneID
4791Protein Accession#
Q00653Gene Name
NFKB2
Gene Alias
LYT-10, LYT10
Gene Description
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Omim ID
164012Gene Ontology
HyperlinkGene Summary
NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. For reviews, see Chen et al. (1999) [PubMed 9895331] and Baldwin (1996) [PubMed 8717528].[supplied by OMIM
Other Designations
OTTHUMP00000020371|OTTHUMP00000059136|nuclear factor of kappa light chain gene enhancer in B-cells 2|nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
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Interactome
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Pathway
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Disease
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