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Last updated: 2021/6/13

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EDA2R monoclonal antibody, clone 4A6B4 

  • Catalog # : MAB21461
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human EDA2R.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 1-138 of human EDA2R.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 32.8
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of Lane 1: HEK293 and Lane 2: EDA2R-hIgGFc transfected HEK293 cell lysates with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461).
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of MOLT4 cells with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461) (Green). Red: Negative Control.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Gene Name:
  • EDA2R
  • Gene Alias:
  • EDA-A2R,EDAA2R,TNFRSF27,XEDAR
  • Gene Description:
  • ectodysplasin A2 receptor
  • Gene Summary:
  • EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq
  • Other Designations:
  • EDA-A2 receptor,OTTHUMP00000023448,X-linked ectodysplasin receptor,X-linked ectodysplasin-A2 receptor,tumor necrosis factor receptor superfamily member XEDAR
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