EDA2R monoclonal antibody, clone 4A6B4
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human EDA2R.
Immunogen
Recombinant protein corresponding to amino acids 1-138 of human EDA2R.
Host
Mouse
Theoretical MW (kDa)
32.8
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: EDA2R-hIgGFc transfected HEK293 cell lysates with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461).Flow Cytometry
Flow cytometric analysis of MOLT4 cells with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461) (Green). Red: Negative Control. -
Gene Info — EDA2R
Entrez GeneID
60401Protein Accession#
Q9HAV5Gene Name
EDA2R
Gene Alias
EDA-A2R, EDAA2R, TNFRSF27, XEDAR
Gene Description
ectodysplasin A2 receptor
Omim ID
300276Gene Ontology
HyperlinkGene Summary
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq
Other Designations
EDA-A2 receptor|OTTHUMP00000023448|X-linked ectodysplasin receptor|X-linked ectodysplasin-A2 receptor|tumor necrosis factor receptor superfamily member XEDAR
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Interactome
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Pathway
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Disease
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