KAT2B monoclonal antibody, clone 7D12C8
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human KAT2B.
Immunogen
Recombinant protein corresponding to amino acids 1-142 of human KAT2B.
Host
Mouse
Theoretical MW (kDa)
93
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Immunocytochemistry (1:200-1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:1000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: KAT2B-hIgGFc transfected HEK293 cell lysates with KAT2B monoclonal antibody, clone 7D12C8 (Cat # MAB21454).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervix cancer with KAT2B monoclonal antibody, clone 7D12C8 (Cat # MAB21454).Immunocytochemistry
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with KAT2B monoclonal antibody, clone 7D12C8 (Cat # MAB21454).Flow Cytometry
Flow cytometric analysis of MOLT4 cells with KAT2B monoclonal antibody, clone 7D12C8 (Cat # MAB21454) (Green). Red: Negative Control. -
Gene Info — KAT2B
Entrez GeneID
8850Protein Accession#
Q92831Gene Name
KAT2B
Gene Alias
CAF, P, P/CAF, PCAF
Gene Description
K(lysine) acetyltransferase 2B
Omim ID
602303Gene Ontology
HyperlinkGene Summary
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq
Other Designations
CREBBP-associated factor|p300/CBP-associated factor
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