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Last updated: 2021/6/13

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KAT2B monoclonal antibody, clone 7D12C8 

  • Catalog # : MAB21454
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human KAT2B.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 1-142 of human KAT2B.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 93
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Immunocytochemistry (1:200-1:1000)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:1000)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of Lane 1: HEK293 and Lane 2: KAT2B-hIgGFc transfected HEK293 cell lysates with KAT2B monoclonal antibody, clone 7D12C8 (Cat # MAB21454).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervix cancer with KAT2B monoclonal antibody, clone 7D12C8 (Cat # MAB21454).
  • Immunocytochemistry
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis with KAT2B monoclonal antibody, clone 7D12C8 (Cat # MAB21454).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of MOLT4 cells with KAT2B monoclonal antibody, clone 7D12C8 (Cat # MAB21454) (Green). Red: Negative Control.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunocytochemistry
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8850
  • Gene Name:
  • KAT2B
  • Gene Alias:
  • CAF,P,P/CAF,PCAF
  • Gene Description:
  • K(lysine) acetyltransferase 2B
  • Gene Summary:
  • CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq
  • Other Designations:
  • CREBBP-associated factor,p300/CBP-associated factor
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