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Last updated: 2021/6/13

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HAVCR2 monoclonal antibody, clone 5A7D12 

  • Catalog # : MAB21446
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human HAVCR2.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 224-301 of human HAVCR2.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 33.4
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of Lane 1: HEK293 and Lane 2: HAVCR2-hIgGFc transfected HEK293 cell lysates with HAVCR2 monoclonal antibody, clone 5A7D12 (Cat # MAB21446).
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis with HAVCR2 monoclonal antibody, clone 5A7D12 (Cat # MAB21446).
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Gene Name:
  • HAVCR2
  • Gene Alias:
  • FLJ14428,KIM-3,TIM3,TIMD3,Tim-3
  • Gene Description:
  • hepatitis A virus cellular receptor 2
  • Gene Summary:
  • CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.[supplied by OMIM
  • Other Designations:
  • T cell immunoglobulin mucin 3,T cell immunoglobulin mucin-3,kidney injury molecule-3
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