HAVCR2 monoclonal antibody, clone 5A7D12
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: HAVCR2-hIgGFc transfected HEK293 cell lysates with HAVCR2 monoclonal antibody, clone 5A7D12 (Cat # MAB21446).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with HAVCR2 monoclonal antibody, clone 5A7D12 (Cat # MAB21446).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human HAVCR2.
Immunogen
Recombinant protein corresponding to amino acids 224-301 of human HAVCR2.
Host
Mouse
Theoretical MW (kDa)
33.4
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: HAVCR2-hIgGFc transfected HEK293 cell lysates with HAVCR2 monoclonal antibody, clone 5A7D12 (Cat # MAB21446).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with HAVCR2 monoclonal antibody, clone 5A7D12 (Cat # MAB21446). -
Gene Info — HAVCR2
Entrez GeneID
84868Protein Accession#
Q8TDQ0Gene Name
HAVCR2
Gene Alias
FLJ14428, KIM-3, TIM3, TIMD3, Tim-3
Gene Description
hepatitis A virus cellular receptor 2
Omim ID
606652Gene Ontology
HyperlinkGene Summary
CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.[supplied by OMIM
Other Designations
T cell immunoglobulin mucin 3|T cell immunoglobulin mucin-3|kidney injury molecule-3
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Interactome
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Disease
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