CD27 monoclonal antibody, clone 3B6D3
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CD27-hIgGFc transfected HEK293 cell lysates with CD27 monoclonal antibody, clone 3B6D3 (Cat # MAB21443).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CD27 monoclonal antibody, clone 3B6D3 (Cat # MAB21443).
Flow Cytometry
Flow cytometric analysis of HL-60 cells with CD27 monoclonal antibody, clone 3B6D3 (Cat # MAB21443) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CD27.
Immunogen
Recombinant protein corresponding to amino acids 20-144 of human CD27.
Host
Mouse
Theoretical MW (kDa)
29.1
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CD27-hIgGFc transfected HEK293 cell lysates with CD27 monoclonal antibody, clone 3B6D3 (Cat # MAB21443).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CD27 monoclonal antibody, clone 3B6D3 (Cat # MAB21443).Flow Cytometry
Flow cytometric analysis of HL-60 cells with CD27 monoclonal antibody, clone 3B6D3 (Cat # MAB21443) (Green). Red: Negative Control. -
Gene Info — CD27
Entrez GeneID
939Protein Accession#
P26842Gene Name
CD27
Gene Alias
MGC20393, S152, T14, TNFRSF7, Tp55
Gene Description
CD27 molecule
Omim ID
186711Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq
Other Designations
CD27 antigen|CD27L receptor|T cell activation antigen CD27|T cell antivation antigen S152|tumor necrosis factor receptor superfamily, member 7
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Interactome
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Pathway
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Disease
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