CCR2 monoclonal antibody, clone 3B6B1
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CCR2.
Immunogen
Recombinant protein corresponding to human CCR2.
Host
Mouse
Theoretical MW (kDa)
41.9
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CCR2-hIgGFc transfected HEK293 cell lysates with CCR2 monoclonal antibody, clone 3B6B1 (Cat # MAB21433).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CCR2 monoclonal antibody, clone 3B6B1 (Cat # MAB21433).Flow Cytometry
Flow cytometric analysis of HL-60 cells with CCR2 monoclonal antibody, clone 3B6B1 (Cat # MAB21433) (Green). Red: Negative Control. -
Gene Info — CCR2
Entrez GeneID
729230Protein Accession#
P41597Gene Name
CCR2
Gene Alias
MGC168006
Gene Description
chemokine (C-C motif) receptor 2-like
Gene Ontology
HyperlinkGene Summary
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq
Other Designations
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Pathway
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Disease
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