ADAM8 monoclonal antibody, clone 2C1F3
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human ADAM8.
Immunogen
Recombinant protein corresponding to amino acids 17-156 of human ADAM8.
Host
Mouse
Theoretical MW (kDa)
88.8
Reactivity
Human
Form
Liquid
Isotype
IgG2a
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Immunocytochemistry (1:200-1:500)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:1000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: ADAM8-hIgGFc transfected HEK293 cell lysates with ADAM8 monoclonal antibody, clone 2C1F3 (Cat # MAB21426).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervix cancer with ADAM8 monoclonal antibody, clone 2C1F3 (Cat # MAB21426).Immunocytochemistry
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with ADAM8 monoclonal antibody, clone 2C1F3 (Cat # MAB21426).Flow Cytometry
Flow cytometric analysis of HL-60 cells with ADAM8 monoclonal antibody, clone 2C1F3 (Cat # MAB21426) (Green). Red: Negative Control. -
Gene Info — ADAM8
Entrez GeneID
101Protein Accession#
P78325Gene Name
ADAM8
Gene Alias
CD156, MGC134985, MS2
Gene Description
ADAM metallopeptidase domain 8
Omim ID
602267Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
CD156a antigen|OTTHUMP00000020792|a disintegrin and metalloproteinase domain 8|cell surface antigen MS2
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Interactome
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Disease
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