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Last updated: 2021/6/6

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IL7R monoclonal antibody, clone 3F5D9 

  • Catalog # : MAB21423
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human IL7R.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 21-239 of human IL7R.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 51.6
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of Lane 1: HEK293 and Lane 2: IL7R-hIgGFc transfected HEK293 cell lysates with IL7R monoclonal antibody, clone 3F5D9 (Cat # MAB21423).
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis with IL7R monoclonal antibody, clone 3F5D9 (Cat # MAB21423).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of HL-60 cells with IL7R monoclonal antibody, clone 3F5D9 (Cat # MAB21423) (Green). Red: Negative Control.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3575
  • Gene Name:
  • IL7R
  • Gene Alias:
  • CD127,CDW127,IL-7R-alpha,IL7RA,ILRA
  • Gene Description:
  • interleukin 7 receptor
  • Gene Summary:
  • The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq
  • Other Designations:
  • CD127 antigen,interleukin 7 receptor alpha chain
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