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SIGLEC5 monoclonal antibody, clone 3F5A3 

  • Catalog # : MAB21412
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human SIGLEC5.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 17-230 of human SIGLEC5.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 60.7
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of Lane 1: HEK293 and Lane 2: SIGLEC5-hIgGFc transfected HEK293 cell lysates with SIGLEC5 monoclonal antibody, clone 3F5A3 (Cat # MAB21412).
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis with SIGLEC5 monoclonal antibody, clone 3F5A3 (Cat # MAB21412).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of HL-60 cells with SIGLEC5 monoclonal antibody, clone 3F5A3 (Cat # MAB21412) (Green). Red: Negative Control.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8778
  • Gene Name:
  • SIGLEC5
  • Gene Alias:
  • CD170,CD33L2,OB-BP2,OBBP2,SIGLEC-5
  • Gene Description:
  • sialic acid binding Ig-like lectin 5
  • Gene Summary:
  • The sialic acid-binding immunoglobulin-like lectins (SIGLECs), such as SIGLEC5, are a subgroup of the immunoglobulin (Ig) superfamily that mediate protein-carbohydrate interactions. They specifically interact with sialic acids in glycoproteins and glycolipids, with each SIGLEC having a particular preference for both the nature of the sialic acid and its glycosidic linkage to adjacent sugars. SIGLECs have similar structures, including extracellular Ig-like domains composed of an N-terminal V-set domain followed by varying numbers of C2-set domains. It appears that all SIGLECs have an unusual arrangement of conserved cysteine residues in the V-set and adjacent C2-set domains. Most SIGLECs are expressed uniquely within the hematopoietic system (Cornish et al., 1998 [PubMed 9731071]).[supplied by OMIM
  • Other Designations:
  • CD33 antigen-like 2,OB binding protein-2,sialic acid-binding immunoglobulin-like lectin 5
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