SIGLEC5 monoclonal antibody, clone 3F5A3
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: SIGLEC5-hIgGFc transfected HEK293 cell lysates with SIGLEC5 monoclonal antibody, clone 3F5A3 (Cat # MAB21412).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with SIGLEC5 monoclonal antibody, clone 3F5A3 (Cat # MAB21412).
Flow Cytometry
Flow cytometric analysis of HL-60 cells with SIGLEC5 monoclonal antibody, clone 3F5A3 (Cat # MAB21412) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human SIGLEC5.
Immunogen
Recombinant protein corresponding to amino acids 17-230 of human SIGLEC5.
Host
Mouse
Theoretical MW (kDa)
60.7
Reactivity
Human
Form
Liquid
Isotype
IgG2a
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: SIGLEC5-hIgGFc transfected HEK293 cell lysates with SIGLEC5 monoclonal antibody, clone 3F5A3 (Cat # MAB21412).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with SIGLEC5 monoclonal antibody, clone 3F5A3 (Cat # MAB21412).Flow Cytometry
Flow cytometric analysis of HL-60 cells with SIGLEC5 monoclonal antibody, clone 3F5A3 (Cat # MAB21412) (Green). Red: Negative Control. -
Gene Info — SIGLEC5
Entrez GeneID
8778Protein Accession#
O15389Gene Name
SIGLEC5
Gene Alias
CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5
Gene Description
sialic acid binding Ig-like lectin 5
Omim ID
604200Gene Ontology
HyperlinkGene Summary
The sialic acid-binding immunoglobulin-like lectins (SIGLECs), such as SIGLEC5, are a subgroup of the immunoglobulin (Ig) superfamily that mediate protein-carbohydrate interactions. They specifically interact with sialic acids in glycoproteins and glycolipids, with each SIGLEC having a particular preference for both the nature of the sialic acid and its glycosidic linkage to adjacent sugars. SIGLECs have similar structures, including extracellular Ig-like domains composed of an N-terminal V-set domain followed by varying numbers of C2-set domains. It appears that all SIGLECs have an unusual arrangement of conserved cysteine residues in the V-set and adjacent C2-set domains. Most SIGLECs are expressed uniquely within the hematopoietic system (Cornish et al., 1998 [PubMed 9731071]).[supplied by OMIM
Other Designations
CD33 antigen-like 2|OB binding protein-2|sialic acid-binding immunoglobulin-like lectin 5
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